Self-explanatory.  I think from time to time about how hard it is for actors to end-up on one hit, much less two.  But quite a few have (playing a bit fast and loose with "star" and "hit" on a few of these). 

Michael Weatherly - NCIS, Bull

Tom Selleck - Magnum P.I., Blue Bloods

Kelsey Grammar - Cheers, Frasier

Ted Danson - Cheers, The Good Place

Julia Louis Dreyfuss (she's the only one I can think of in more than 2) - SNL, Seinfeld, Veep, New Adventures of Old Christine

Tim Allen - Home Improvement, Last Man Standing

Ted Danson was in Becker, as well. Not necessarily a hit, but 6 seasons is nothing to sneeze at.

Bob Newhart - The Bob Newhart Show, Newhart

Andy Griffith - Andy Griffith Show, Matlock.

posted by queencitybuckeye

Andy Griffith

Good one.

John Ritter - Three's Company and 8 Simple Rules

Michael Emerson - Lost, Person of Interest

James Spader - Boston Legal, The Blacklist, and I won't count his season on The Office

posted by gut

Self-explanatory.  I think from time to time about how hard it is for actors to end-up on one hit, much less two.  But quite a few have (playing a bit fast and loose with "star" and "hit" on a few of these). 

Michael Weatherly - NCIS, Bull

Tom Selleck - Magnum P.I., Blue Bloods

Kelsey Grammar - Cheers, Frasier

Ted Danson - Cheers, The Good Place

Julia Louis Dreyfuss (she's the only one I can think of in more than 2) - SNL, Seinfeld, Veep, New Adventures of Old Christine

Tim Allen - Home Improvement, Last Man Standing

To be fair, Grammar wasn't a lead on Cheers. Danson was. Frasier was a support character on Cheers and got a spin off show.

Neil Patrick Harris-Doogie Houser MD, How I Met Your Mother (he was the star of that show).

Ed O'Neill-Married With Children, Modern Family

Bryan Cranston: Malcolm in the Middle, Breaking Bad 

Elizabeth Moss: Mad Men, Handmaid's Tale

Alison Brie: Glow, Community 

Courtney Cox-Friends, Cougar Town

Matt LeBlanc-Friends, Man of the House, Joey

Mila Kunis-That 70's Show, Family Guy (voice of Meg)

Laura Prepon-That 70's Show, Orange is the New Black

Timothy Olyphant: Deadwood, Justified 

Kyle Chandler - Early Edition, Friday Night Lights, Bloodline.

Walter Goggins - The Shield, Justified, could maybe count Vice Principals

Michael Chiklis - The Commish, The Shield

Kiefer Sutherland - 24, Designated Survivor

posted by jmog

To be fair, Grammar wasn't a lead on Cheers. Danson was. Frasier was a support character on Cheers and got a spin off show.

I guess I meant regular/main character, not necessarily the lead.  Seinfeld would be a good example - George and Jerry's parents would count, but probably not Uncle Leo.  Newman and maybe Peterman, but probably not Puddy or Steinbrenner.

Michael Landon - Little House on the Prairie,  Highway to Heaven

John Larriquette

Night Court 

The John Larriquette Show

Boston Legal

Vicki Lawerence/Carol Burnett ....Carol Burnett Show and Mama’s Family

Jim Nabors

Gomer Pyle/Andy Griffith Show

Ron Howard (Hapoy Days/Andy Griffith Show)

Kaley Cucuo....8 Simple Rules/BBT

posted by gut

I guess I meant regular/main character, not necessarily the lead.  Seinfeld would be a good example - George and Jerry's parents would count, but probably not Uncle Leo.  Newman and maybe Peterman, but probably not Puddy or Steinbrenner.

Outside of the main 4, and surprisingly, the cashier lady at Monk's, Newman was in the most episodes (45). Puddy was only in 10.

The Hoff -- Knight Rider, Baywatch

posted by justincredible

Outside of the main 4, and surprisingly, the cashier lady at Monk's, Newman was in the most episodes (45). Puddy was only in 10.

Puddy was only in 10?  Wow.  He had to have been mentioned in at least 10 others, though?

If you bet me Newman was only in 45 out of 173 shows, I would have definitely taken the over.

posted by jmog

Neil Patrick Harris-Doogie Houser MD, How I Met Your Mother (he was the star of that show).

 

 

 He also had a starring role (not necessarily THE star) in American Horror Story: Freak Show

posted by bigorangebuck22

Michael Landon - Little House on the Prairie,  Highway to Heaven

Bonanza.

Lucille Ball.

posted by Ironman92

Kaley Cucuo....8 Simple Rules/BBT

Somebody that good deserves to have her name spelled correctly. 

Cuoco

So speaking of BBT......Jim Parsons and Young Sheldon. 

Richard Dean Anderson - Macgyver and Stargate